A complete list of publications by Dr. Bhat can be reviewed here.
Trajectories of patients relisted for liver transplantation
Qazi Arisar FA, Varghese R, Chen S, Xu W, Selzner M, McGilvray I, Sayed B, Reichman T, Shwaartz C,
Cattral M, Ghanekar A, Sapisochin G, Jaeckel E, Tsien C, Selzner N, Lilly L, Bhat M. (2024). Ann Hepatol. Jan-Feb;29(1): 101168.
Defining an approach for therapeutic strategies in metabolic dysfunction-associated steatotic liver disease after liver transplantation
Siddiqui MS, Muthiah M, Satapathy SK, Patidar K, Bhat M, Brandman D, Watt KD, Rinella M. (2023). Hepatology. Dec 13.
Evaluation & management of non-alcohol / non-metabolic dysfunction-associated steatohepatitis.
Qasim Khan M, Hassan S, Lizaola-Mayo BC, Bhat M, Watt KD. (2023). Hepatology. Nov 7: In Press
A Comprehensive Review of Liver Allograft Fibrosis and Steatosis: From Cause to Diagnosis.
Rabindranath M, Zaya R, Prayitno K, Orchanian-Cheff A, Patel K, Jaeckel E, Bhat M. (2023). Transplant
Direct.Oct 16;9(11): e1547.
RNA nanomedicine in liver diseases.
Bakrania A, Mo Y, Zheng G, Bhat M. Hepatology. 2023 Sep 19. doi: 10.1097/HEP.0000000000000606. Epub ahead of print.
Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients.
Arisar FAQ, Chen S, Chen C, Shaikh N, Karnam RS, Xu W, Asrani SK, Galvin Z, Hirschfield G, Patel K, Tsien C, Selzner N, Cattral M, Lilly L, Bhat M. Aging (Albany NY). 2023 Sep 2;15(17):8594-8612. doi: 10.18632/aging.204982. Epub 2023 Sep 2.
Repurposing UDCA, an FXR Inhibitor, to Prevent SARS-Cov-2 Infection.
Prayitno K, Bhat M. Gastroenterology. 2023 May;164(6):1019-1020. doi: 10.1053/j.gastro.2023.01.014. Epub 2023 Jan 19.
Impact of Living Donor Liver Transplantation on Long-term Cardiometabolic and Graft outcomes in cirrhosis due to Nonalcoholic steatohepatitis.
Karnam RS, Azhie A, Yang C, Rogalsky A, Chen S, Xu W, Patel K, Selzner N, Lilly L, Cattral M, Bhat M.
(2023). Clinical Transplantation. 2023 May 4: e15008. Published. Refereed?: Yes
Hybrid Coronary Artery Revascularization Before Liver Transplantation: A Case Report.
Martinez-Perez S, Davierwala P, McCluskey SA, Kalra S, Luzzi C, McGilvray I, Kalogeropoulos G, Bhat M, Neethling E. J Cardiothorac Vasc Anesth. 2023 Jul 7:S1053-0770(23)00465-2. doi: 10.1053/j.jvca.2023.07.005. Epub ahead of print.
Exception points for liver transplantation: A Canadian review.
Congly SE, Marquez V, Bhanji RA, Bhat M, Wong P, Huard G, Zhu JH, Brahmania M. Can Liver J. 2023 Jul 26;6(2):201-214. doi: 10.3138/canlivj-2022-0026
Adeno-Associated Virus 2 Implicated in Recent Clusters of Unexplained Acute Severe Hepatitis in Children.
Sutton H, Bhat M. Gastroenterology. 2023 Sep;165(3):803-804. doi: 10.1053/j.gastro.2023.04.022. Epub 2023 Apr 29
Proteomic Panels for Alcohol-Associated Liver Disease: Accurate, but Different Enough From Existing Clinical Tests?
Mezzacappa C, Bhat M. Gastroenterology. 2023 Sep 6:S0016-5085(23)04977-6. doi: 10.1053/j.gastro.2023.09.002. Epub ahead of print.
Genomic Analysis of Hair From Celebrated Composer Provides Insight Into Liver Disease Susceptibility.
Naimimohasses S, Bhat M. Gastroenterology. 2023 Aug;165(2):514. doi: 10.1053/j.gastro.2023.04.020. Epub 2023 Apr 29.
Automated fatty liver disease detection in point-of-care ultrasound B-mode images.
Ibrahim MN, Blázquez-García R, Lightstone A, Meng F, Bhat M, El Kaffas A, Ukwatta E. J Med Imaging (Bellingham). 2023 May;10(3):034505. doi: 10.1117/1.JMI.10.3.034505
Transcriptomic changes in liver transplant recipients with non-alcoholic steatohepatitis indicate dysregulation of wound healing.
Pellegrina D, Prayitno K, Azhie A, Pasini E, Baciu C, Fischer S, Reimand J, Bhat M. Front Endocrinol (Lausanne). 2023 May 8;14:1111614. doi: 10.3389/fendo.2023.1111614.
Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer metastases.
Bakrania A, Joshi N, Zhao X, Zheng G, Bhat M. Pharmacol Res. 2023 Mar;189:106706. doi: 10.1016/j.phrs.2023.106706. Epub 2023 Feb 20.
Development of a Radiomics-Based Model to Predict Graft Fibrosis in Liver Transplant Recipients: A Pilot Study.
Qazi Arisar FA, Salinas-Miranda E, Ale Ali H, Lajkosz K, Chen C, Azhie A, Healy GM, Deniffel D, Haider MA, Bhat M. Transpl Int. 2023 Sep 1;36:11149. doi: 10.3389/ti.2023.11149.
Impact of living donor liver transplantation on long-term cardiometabolic and graft outcomes in cirrhosis due to nonalcoholic steatohepatitis.
Karnam RS, Azhie A, Yang C, Rogalsky A, Chen S, Xu W, Patel K, Selzner N, Lilly L, Cattral M, Bhat M. Clin Transplant. 2023 Sep;37(9):e15008. doi: 10.1111/ctr.15008. Epub 2023 May 4.
Predicting the outcome of liver transplantation in patients with non-alcoholic steatohepatitis cirrhosis: The NASH LT risk-benefit calculator.
Karnam RS, Punchhi G, Mitsakakis N, Chen S, Saracino G, Lilly L, Asrani SK, Bhat M. Clin Transplant. 2023 Apr;37(4):e14930. doi: 10.1111/ctr.14930. Epub 2023 Feb 24.
Living Donor Liver Transplantation can Address Disparities in Transplant Access for Patients with Primary Sclerosing Cholangitis
Onofrio F, Katina Zheng K, Xu C, Chen S, Xu W, Vyas M, Bingham K, Patel K, Lilly L, Cattral M, Selzner
N, Jaeckel E, Tsien C, Gulamhusein A, Hirschfield GM, Bhat M. (2023). Hepatology Communications. Aug 3;7(8): e0219.
A Deep Learning Framework for Personalized Dynamic Diagnosis of Graft Fibrosis after Liver Transplantation using Longitudinal Data
Azhie A, Sharma D, Sheth P, Qazi-Arisar F, Zaya R, Naghibzadeh M, Duan K, Fischer S, Patel K, Tsien C, Selzner N, Lilly L, Jaeckel E, Xu W, Bhat M. Lancet Digital Health, 2023(published online May 18). https://doi.org/10.1016/S2589-7500(23)00068-7
A Multi-Class Neural Network Machine Learning Algorithm to Diagnose Graft Pathology in Liver Transplant Recipients.
Gotlieb N*, Sharma D*, Chahal D*, Naghibzadeh M, Azhie A, Keshavarzi S, Duan K, Lilly L, Selzner N, Tsien C, Jaeckel E, Xu W, Bhat M. SSRN: https://ssrn.com/abstract=4323740 or http://dx.doi.org/10.2139/ssrn.4323740
Artificial Intelligence, Machine Learning, and Deep Learning in Liver Transplantation.
Bhat M, Rabindranath M, Sordi Chara B, Simonetto DA. Journal of Hepatology. 2023;78(6):119-136.
Artificial intelligence applied to omics data in liver diseases: Enhancing clinical predictions.
Baciu C, Xu C, Alim M, Prayitno K, Bhat M. A Front Artif Intell. 2022 Nov 15;5:1050439. doi: 10.3389/frai.2022.1050439. PMID: 36458100; PMCID: PMC9705954.
The promise of artificial intelligence for predictive biomarkers in hepatology.
Bhat M, Rabindranath M. Hepatol Int. 2022 Jun;16(3):523-525. doi: 10.1007/s12072-022-10342-7. Epub 2022 May 16. PMID: 35575965.
A Promising Solution for Rescuing Organs After Prolonged Ischemia.
Nguyen-Lefebvre AT, Bhat M. Gastroenterology. 2023 Apr;164(4):696-697. doi: 10.1053/j.gastro.2022.11.016. Epub 2022 Nov 15.
What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2022? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.
Bhat M, Dondossola D, Varghese R, Czigany Z, Emamaullee J, Ghinolfi D, Al-Adra D, Bonaccorsi-Riani E, Pang L, Boteon YL, Brüggenwirth I, Pavan-Guimaraes J, Ho CM, Yuksel M, Zarrinpar A, Abdelrahim M, Barbas AS, Mas V, Selzner M, Martins PN.Transplantation. 2022 Dec 23. doi: 10.1097/T
Medical Assistance in Dying (MAiD) as a Source of Liver Grafts: Honouring the Ultimate Gift.
Ray S, Torres-Hernandez A, Bleszynski MS, Parmentier C, McGilvray I, Sayed BA, Shwaartz C, Cattral M, Ghanekar A, Sapisochin G, Tsien C, Selzner N, Lilly L, Bhat M, Jaeckel E, Selzner M, Reichman T.Ann Surg. 2022 Dec 14. doi: 10.1097/SLA.0000000000005775. Online ahead of print.PMID: 36515405
Enhanced recovery for liver transplantation: recommendations from the 2022 International Liver Transplantation Society consensus conference.
Pollok JM, Tinguely P, Berenguer M, Niemann CU, Raptis DA, Spiro M; ERAS4OLT.org collaborative.Lancet Gastroenterol Hepatol. 2023 Jan;8(1):81-94. doi: 10.1016/S2468-1253(22)00268-0.PMID: 36495912 Review.
Artificial intelligence applied to omics data in liver diseases: Enhancing clinical predictions.
Baciu C, Xu C, Alim M, Prayitno K, Bhat M. Front Artif Intell. 2022 Nov 15;5:1050439. doi: 10.3389/frai.2022.1050439. eCollection 2022.PMID: 36458100 Free PMC article. Review.
OrganEx: A Promising Solution for Rescuing Organs After Prolonged Ischemia.
Nguyen-Lefebvre AT, Bhat M. Gastroenterology. 2022 Nov 15:S0016-5085(22)01277-X. doi: 10.1053/j.gastro.2022.11.016. Online ahead of print.PMID: 36400180 No abstract available.
Long-term outcomes of retransplantation after live donor liver transplantation: A Western experience.
Ivanics T, Limkemann A, Patel MS, Claasen MPAW, Rajendran L, Choi WJ, Shwaartz C, Selzner N, Lilly L, Bhat M, Tsien C, Selzner M, McGilvray I, Sayed B, Reichman T, Cattral M, Ghanekar A, Sapisochin G.Surgery. 2022 Nov 2:S0039-6060(22)00796-6. doi: 10.1016/j.surg.2022.09.022. Online ahead of print.PMID: 36334982
Achieving tolerance modifies cancer susceptibility profiles in liver transplant recipients.
Bhat M, Pasini E, Patel P, Yu J, Baciu C, Kurian SM, Levitsky J.Cancer Med. 2022 Oct 7. doi: 10.1002/cam4.5271. Online ahead of print.PMID: 36205189 Free article.
Divergent trajectories of lean vs obese non-alcoholic steatohepatitis patients from listing to post-transplant: A retrospective cohort study.
Qazi-Arisar FA, Uchila R, Chen C, Yang C, Chen SY, Karnam RS, Azhie A, Xu W, Galvin Z, Selzner N, Lilly L, Bhat M. World J Gastroenterol. 2022 Jul 14;28(26):3218-3231. doi: 10.3748/wjg.v28.i26.3218.PMID: 36051335
The promise of machine learning applications in solid organ transplantation.
Gotlieb N, Azhie A, Sharma D, Spann A, Suo NJ, Tran J, Orchanian-Cheff A, Wang B, Goldenberg A, Chassé M, Cardinal H, Cohen JP, Lodi A, Dieude M, Bhat M.NPJ Digit Med. 2022 Jul 11;5(1):89. doi: 10.1038/s41746-022-00637-2.PMID: 35817953 Free PMC article. Review.
Predictors of patient survival following liver transplant in non-alcoholic steatohepatitis: A systematic review and meta-analysis.
Minich A, Arisar FAQ, Shaikh NS, Herman L, Azhie A, Orchanian-Cheff A, Patel K, Keshavarzi S, Bhat M.EClinicalMedicine. 2022 Jul 1;50:101534. doi: 10.1016/j.eclinm.2022.101534. eCollection 2022 Aug.PMID: 35812989
The promise of artificial intelligence for predictive biomarkers in hepatology.
Bhat M, Rabindranath M.Hepatol Int. 2022 Jun;16(3):523-525. doi: 10.1007/s12072-022-10342-7. Epub 2022 May 16.PMID: 35575965 No abstract available.
Multi-omic Characterization of COVID Hepatitis.
Bhat M.Gastroenterology. 2022 Jul;163(1):335. doi: 10.1053/j.gastro.2022.05.004. Epub 2022 May 2.PMID: 35513009 Free PMC article. No abstract available.
Deep learning and the future of the Model for End-Stage Liver Disease-sodium score.
Cooper M, Krishnan RG, Bhat M.Liver Transpl. 2022 Jul;28(7):1128-1130. doi: 10.1002/lt.26485. Epub 2022 May 4.PMID: 35437897 No abstract available.
PFeasibility of a Home-Based Exercise Program for Managing Posttransplant Metabolic Syndrome in Lung and Liver Transplant Recipients: Protocol for a Pilot Randomized Controlled Trial.
Rozenberg D, Santa Mina D, Nourouzpour S, Camacho Perez E, Stewart BL, Wickerson L, Tsien C, Selzner N, Shore J, Aversa M, Woo M, Holdsworth S, Prevost K, Park J, Azhie A, Huszti E, McLeod E, Dales S, Bhat M.JMIR Res Protoc. 2022 Mar 23;11(3):e35700. doi: 10.2196/35700.PMID: 35319467 Free PMC article.
Phase II clinical trial of cabozantinib for the treatment of recurrent hepatocellular carcinoma after liver transplantation.
Azhie A, Grant RC, Herman M, Wang L, Knox JJ, Bhat M.Future Oncol. 2022 Jun;18(18):2173-2191. doi: 10.2217/fon-2021-1635. Epub 2022 Mar 15.PMID: 35287469 Review.
Development and validation of an ensemble machine learning framework for detection of all-cause advanced hepatic fibrosis: a retrospective cohort study.
Sarvestany SS, Kwong JC, Azhie A, Dong V, Cerocchi O, Ali AF, Karnam RS, Kuriry H, Shengir M, Candido E, Duchen R, Sebastiani G, Patel K, Goldenberg A, Bhat M.Lancet Digit Health. 2022 Mar;4(3):e188-e199. doi: 10.1016/S2589-7500(21)00270-3.PMID: 35216753 Free article.
Nanomedicine in Hepatocellular Distinctive clinical and genetic features of lean vs overweight fatty liver disease using the UK Biobank.
Chahal D, Sharma D, Keshavarzi S, Arisar FAQ, Patel K, Xu W, Bhat M.Hepatol Int. 2022 Apr;16(2):325-336. doi: 10.1007/s12072-022-10304-z. Epub 2022 Feb 18.PMID: 35178663
Nanomedicine in Hepatocellular Carcinoma: A New Frontier in Targeted Cancer Treatment.
Bakrania A, Zheng G, Bhat M.Pharmaceutics. 2021 Dec 25;14(1):41. doi: 10.3390/pharmaceutics14010041.PMID: 35056937 Free PMC article. Review.
Application of machine learning in liver transplantation: a review.
Tran J, Sharma D, Gotlieb N, Xu W, Bhat M.Hepatol Int. 2022 Jun;16(3):495-508. doi: 10.1007/s12072-021-10291-7. Epub 2022 Jan 12.PMID: 35020154 Review.
Machine Learning Approach to Classify Cardiovascular Disease in Patients With Nonalcoholic Fatty Liver Disease in the UK Biobank Cohort.
Sharma D, Gotlieb N, Farkouh ME, Patel K, Xu W, Bhat M.J Am Heart Assoc. 2022 Jan 4;11(1):e022576. doi: 10.1161/JAHA.121.022576. Epub 2021 Dec 20.PMID: 34927450 Free PMC article.
Estrogen Receptor 1 Contributes to Sex-Specific Differences in Hepatocellular Carcinoma through Inhibition of Wnt signaling.
Bhat M, Pasini E, Pastrello C, Angeli M, Kotlyar M, Tokar T, Jurisica I. Frontiers in Oncology. Published November 2021
Application of Machine Learning in Liver Transplantation.
Yang J, Sharma D, Bhat M. Accepted, Hepatology International November 2021.
Sex Disparity in Liver Transplant and Access to Living Donation.
Karnam RS, Chen S, Xu W, Chen C, Elangainesan P, Ghanekar A, McGilvray I, Reichman T, Sayed B, Selzner M, Sapisochin G, Galvin Z, Hirschfield G, Asrani SK, Selzner N, Cattral M, Lilly L, Bhat M. JAMA Surg. Nov 2021.
Combined Proteomic/Transcriptomic signature of ALDH1A1, LGALS3, LGALS3BP is Associated with Recurrence Post-Liver Transplantation for Hepatocellular Carcinoma Beyond Milan. Clinical Proteomics.
Bhat M, Clotet-Freixas S, Baciu C, Pasini E, Hammad A, Ivanics T, Reid S, Azhie A, Angeli M, Ghanekar A, Fischer S, Sapisochin G, Konvalinka A. Nov 2021.
Liver Retransplantation Using Living Donor Grafts: A Western Experience.
Patel MS, Ghanekar A, Sayed BA, Sapisochin G, McGilvray I, Raschzok N, Reichman T, Selzner M, Galvin Z, Bhat M, Stunguris J, Ng VL, Lilly L, Selzner N, Cattral M. Liver Transpl. Oct 2021.
Metabolic Complications in Liver Transplantation Recipients: How We Can Optimize Long-Term Survival.
Azhie A, Sheth P, Hammad A, Woo M, Bhat M. Liver Transpl. Oct 2021.
Clinical Practice Guideline for Solid Organ Donation and Transplantation During the COVID-19 Pandemic.
Weiss MJ, Hornby L, Foroutan F, Belga S, Bernier S, Bhat M, Buchan CA, Gagnon M, Hardman G, Ibrahim M, Luo C, Luong ML, Mainra R, Manara AR, Sapir-Pichhadze R, Shalhoub S, Shaver T, Singh JM, Srinathan S, Thomas I, Wilson LC, Wilson TM, Wright A, Mah A. Transplant Direct. Sept 2021.
Results of Early Transplantation for Alcohol-Related Cirrhosis: Integrated Addiction Treatment with Low Rate of Relapse.
Carrique L, Quance J, Tan A, Abbey S, Sales I, Lilly L, Bhat M, Galvin Z, Cattral M, Ghanekar A, McGilvray I, Reichman T, Sapisochin G, Sayed B, Selzner M, Lynch MJ, Selzner N. Gastroenterology. Aug 2021.
Early Allograft Dysfunction After Liver Transplantation With Donation After Circulatory Death and Brain Death Grafts: Does the Donor Type Matter?
Mazilescu LI, Kotha S, Ghanekar A, Lilly L, Reichman TW, Galvin Z, Cattral MS, Bhat M, McGilvray ID, Sapisochin G, Sayed B, Selzner M, Selzner N. Transplant Direct. July 2021.
Long-Term Outcomes of Pediatric Living versus Deceased Donor Liver Transplant Recipients: A Systematic Review and Meta-analysis.
Shingina A, Vutien P, Uleryk E, Shah PS, Renner E, Bhat M, Pai A, Tinmouth J, Kim J. Liver Transpl. July 2021.
Systematic review and meta-analysis of post-transplant diabetes mellitus in liver transplant recipients.
Lawendy B, Srinathan S, Kotha S, Gomes C, Misra S, Yu J, Orchanian-Cheff A, Tomlinson G, Bhat M. Clin Transplant. July 2021.
Normothermic Ex Situ Liver Perfusion Enhances Mitochondrial Function of DCD Grafts as Evidenced by High-throughput Metabolomics.
Bhat M, Linares-Cervantes I, Pasini E, Patel P, Goto T, Noguchi Y, Mazilescu L, Urbanellis P, Selzner M, Selzner N. Transplantation. July 2021.
Single-Center North American Experience of Liver Transplantation in Autoimmune Hepatitis: Infrequent Indication but Good Outcomes for Patients.
de Quadros Onofrio F, Neong E, Adebayo D, Kollmann D, Adeyi OA, Fischer S, Hirschfield GM, Hansen BE, Bhat M, Galvin Z, Lilly LB, Selzner N. J Can Assoc Gastroenterol. July 2021.
Effective Detection of Compensated Cirrhosis Using Machine Learning.
Sabet Sarvestany S, Kwong J, Cerocchi O, Ahmed Ali F, Karnam R, Kuriry H,Shengir M, Candido E, Duchen R, Patel K, Sebastiani G, Goldenberg A, Bhat M. Lancet Digital Health. 2021 Jun 6.
The Impact of Primary Liver Disease and Social Determinants in a Mixed Donor Liver Transplant Program: A Single-Center Analysis.
Leung KK, Kim A, Hansen BE, Lilly L, Selzner N, Patel K, Bhat M, Hirschfield GM, Galvin Z. Prog Transplant. June 2021.
Idiopathic Fulminant Graft Failure Rescued by Urgent ABO-Incompatible Liver Transplantation. Prog Transplant.
Qazi-Arisar FA, Uchila R, Limkemann A, Galvin Z, Monajemzadeh M, Cattral M, Tinckam K, Sayad B, Bhat M. Prog Transplant. June 2021.
Long-term mortality risk stratification of liver transplant recipients: real-time application of deep learning algorithms on longitudinal data.
Nitski O, Azhie A, Qazi-Arisar FA, Wang X, Ma S, Lilly L, Watt KD, Levitsky J, Asrani SK, Lee DS, Rubin BB, Bhat M, Wang B. Lancet Digit Health. May 2021.
The hippo pathway: A master regulator of liver metabolism, regeneration, and disease.
Nguyen-Lefebvre AT, Selzner N, Wrana JL, Bhat M. FASEB J. May 2021.
Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection.
Deppermann C, Peiseler M, Zindel J, Zbytnuik L, Lee WY, Pasini E, Baciu C, Matelski J, Lee Y, Kumar D, Humar A, Surewaard B, Kubes P, Bhat M. Hepatology. May 2021.
Transcriptomic investigation reveals donor-specific gene signatures in human lung transplants.
Baciu C, Sage A, Zamel R, Shin J, Bai XH, Hough O, Bhat M, Yeung JC, Cypel M, Keshavjee S, Liu M. Eur Respir J. April 2021.
REmote moBile Outpatient mOnitoring in Transplant (Reboot) 2.0: a randomized control trial protocol
Murray KR, Foroutan F, Amadio J, Posada JD, Kozuszko S, Duhamel J, Tsang K, Farkouh ME, McDonald M, Billia F, Barber E, Hershman SG, Bhat M, Tinckam KJ, Ross HJ, McIntosh C, Moayedi Y. JMIR Res Protoc. April 2021.
Long-term mortality risk stratification of liver transplant recipients: real-time application of deep learning algorithms on longitudinal data.
Osvald Nitski, Amirhossein Azhie, Fakhar Ali Qazi-Arisar, Xueqi Wang, Shihao Ma, Leslie Lilly, Kymberly D Watt, Josh Levitsky, Sumeet K Asrani, Douglas S Lee, Barry B Rubin, Mamatha Bhat*, Bo Wang*. Lancet Digit Health. April 2021.
ActiveDriverDB: Interpreting Genetic Variation in Human and Cancer Genomes Using Post-translational Modification Sites and Signaling Networks (2021 Update).
Krassowski M, Pellegrina D, Mee MW, Fradet-Turcotte A, Bhat M, Reimand J. Front Cell Dev Biol. 2021;9:626821. March 2021.
Integrative analysis of layers of data in hepatocellular carcinoma reveals pathway dependencies
Bhat M, Pasini E, Pastrello C, Rahmati S, Angeli M, Kotlyar M, Ghanekar A, Jurisica I.World J Hepatol. 2021;13(1):94-108.
Predicting Long-term Survival after liver transplantation in patients with NASH cirrhosis.
Karnam RS, Mitsakakis N, Saracino G, Lilly L, Asrani SK, Bhat M. Clin Gastroenterol Hepatol. doi.org/10.1016/j.cgh.2021.01.021. 2021 Jan 16:S1542-3565(21)00071-9.
Long- Term Risk Stratification of Liver Transplant Recipients: Real-time Application of Deep Learning Algorithms on Longitudinal Data.
Nitski O, Azhie A, Qazi-Arishar F A, Lilly L, Watt K, Levitsky J, Asrani S, Bhat M*, Wang B*. Lancet Digital Health. Accepted, Jan 2021.
Metabolic Consequences of Solid Organ Transplantation.
Bhat M, Usmani SE, Azhie A, Woo M. Endocrine Reviews. 2020 Nov 28. doi: 10.1210/endrev/bnaa030. Vol. XX, No. XX, 1-27.
Identifying Modifiable Predictors of Long-term Survival in Liver Transplant Recipients with Diabetes Using Machine Learning. Liver Transplantation
Yasodhara A, Dong V, Azhie A, Goldenberg A, Bhat M. 2020 Oct 28. doi.org/10.1002/lt.25930.
Transcriptomic investigation reveals donor specific gene signatures in human lung transplants.
Baciu C, Sage A, Zamel R, Shin J, Bai XH, Hough O, Bhat M, Yeung JC, Cypel M, Keshavjee S, Liu M. Eur Respir J. DOI: 10.1183/13993003.00327-2020
Enteric dysbiosis in liver and kidney transplant recipients: a systematic review.
Sivaraj S, Chan A, Pasini E, Chen E, Lawendy B, Verna E, Watt E, Bhat M. Transplant International. 2020 Jul 8; Online(July 8th).
Renal dysfunction after liver transplantation: effect of donor type.
Kollmann, D., Neong, S.F., Rosales, R., Hansen, B.E., Sapisochin, G., McCluskey, S., Bhat, M., Cattral, M.S., Lilly, L., McGilvray, I.D., Ghanekar, A., Grant, D.R., Selzner, M., Wong, F.S. and Selzner, N. (2020). Liver Transpl. Accepted Author Manuscript. 2020 Mar 19.
Lipoprotein-like Nanoparticle carrying siRNA against SALL4 effectively targets Hepatocellular Carcinoma cells and decreases Tumor burden.
Cruz W, Huang H, Barber B, Pasini E, Zheng G, Chen J, Bhat M. Hepatology Communications. 2020 Jan 10. In Press.
Applying Machine Learning in Liver Disease & Transplantation: A Comprehensive Review.
Spann A, Yasodhara A, Kang J, Watt K, Wang B, Goldenberg A, Bhat M. [published online ahead of print, 2020 Jan 6]. Hepatology. 2020;10.1002/hep.31103.
Diabetogenic Effects of Immunosuppression: An Integrative Analysis.
Bhat M, Pasini E, Das A, Baciu C, Angeli M, Humar A, Watt KD, Allard J. Transplantation. 2020 Jan 4;104(1).
The impact of preexisting and posttransplant diabetes mellitus after transplantation on outcomes after liver transplantation.
Aravinthan A, Doyle A, Galvin Z, Rajakumar R, Selzner N, Lilly L, Bhat M. Transplantation. 2019 Apr.
Live Donor Liver Transplantation for Patients with Hepatocellular Carcinoma Offers Increased Survival vs. Deceased Donation.
Goldaracena N, Gorgen A, Doyle A, Hansen BE, Tomiyama K, Zhang W, Ghanekar A, Lilly L, Cattral M, Galvin Z, Selzner M, Bhat M, Selzner N, McGilvray I, Greig PD, Grant DR, Sapisochin G. J Hepatol. 2019 Jan 7.
Predictors of De Novo Nonalcoholic Fatty Liver Disease After Liver Transplantation and Associated Fibrosis.
Galvin Z, Rajakumar R, Chen E, Adeyi O, Selzner M, Grant D, Sapisochin G, Greig P, Cattral M, McGilvray I, Ghanekar A, Selzner N, Lilly L, Patel K, Bhat M. Liver Transpl. 2019 Jan 1;25(1):56-67.
New-Onset Diabetes and Preexisting Diabetes Are Associated With Comparable Reduction in Long-Term Survival After Liver Transplant: A Machine Learning Approach.
Bhat V, Tazari M, Watt KD, Bhat M. Mayo Clin Proc. 2018 Dec 1;93(12):1794-1802.
Living Donor Liver Transplantation Using Selected Grafts With 2 Bile Ducts Compared With 1 Bile Duct Does Not Impact Patient Outcome.
Kollmann D, Goldaracena N, Sapisochin G, Linares I, Selzner N, Hansen BE, Bhat M, Cattral MS, Greig PD, Lilly L, McGilvray ID, Ghanekar A, Grant DR, Selzner M. Liver Transpl. 2018 Nov 1;24(11):1512-1522.
The Basis of Liver Regeneration: a Systems Biology approach.
Bhat M, Pasini E, Baciu C, Angeli M, Humar A, Macparland S, Feld J, McGilvray I. Annals of Hepatology. 2018 Oct.
Immunosuppression, Race, and Donor-Related Risk Factors Affect De novo Cancer Incidence Across Solid Organ Transplant Recipients.
Bhat M, Mara K, Dierkhising R, Watt K. Mayo Clinic Proceedings. 2018 Sep 4;93(9):1236-1246.
Splenectomy as Flow Modulation Strategy and Risk Factors of De Novo Portal Vein Thrombosis in Adult-to-Adult Living Donor Liver Transplantation.
Linares I, Goldaracena N, Rosales R, Maza L, Kaths M, Kollmann D, Echeverri J, Selzner N, McCluskey SA, Sapisochin G, Lilly LB, Greig P, Bhat M, Ghanekar A, Cattral M, McGilvray I, Grant D, Selzner M. Liver Transpl. 2018 Sep;24(9):1209-1220.
Liver transplantation for NASH-related hepatocellular carcinoma versus non-NASH etiologies of hepatocellular carcinoma.
Sadler EM, Mehta N, Bhat M, Ghanekar A, Greig PD, Grant DR, Yao F, Sapisochin G. Transplantation. 2018 Apr 10;102(4):640-647.
Epigenetic basis of hepatocellular carcinoma: A network-based integrative meta-analysis
Bhat V, Srinathan S, Pasini E, Angeli M, Chen E, Baciu C, Bhat M. World Journal of Hepatology. 2018 Jan 27;10(1):155-165.
Gender, Race and Disease Etiology Predict De Novo Malignancy Risk following Liver Transplantation: Insights for Future Individualized Cancer Screening Guidance
Bhat M, Mara K, Dierkhising R, Watt K. Transplantation. 2018 Jan 26. Impact Factor 3.678.
Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis.
Baciu C, Pasini E, Angeli M, Schwenger K, Afrin J, Humar A, Fischer S, Patel K, Allard J, Bhat M. PLoS One. 2017 Dec 7;12(12):e0189223.
Characteristics of liver transplant candidates delisted following recompensation and predictors of such delisting in alcohol-related liver disease: a case-control study.
Aravinthan AD, Barbas AS, Doyle AC, Tazari M, Sapisochin G, Cattral MS, Ghanekar A, McGilvray ID, Selzner M, Greig PD, Bhat M, Selzner N, Grant DR, Lilly LB, Renner EL. Transplant International. 2017 Nov 30;30(11):1140-1149.
Performance of Transient Elastography and Serum Fibrosis Biomarkers for Non-Invasive Evaluation of Recurrent Fibrosis after Liver Transplantation: a Meta-analysis
Bhat M, Tazari M, Sebastiani G. PLOS One. 2017 Sep 27;12(9):e018519.
Effect of Immunosuppression on the Intestinal Microbiome: Implications for Post-transplant complications.
Bhat M, TPasini E, Copeland J, Renner E, Angeli M, Allard J, Guttman D, Humar A. Scientific Reports. 2017 Aug 31;7(1):10277.
Liver Transplantation is a Preferable Alternative to Palliative Therapy for Selected Patients with Advanced Hepatocellular Carcinoma.
Aravinthan AD, Bruni SG, Doyle AC, Thein HH, Goldaracena N, Issachar A, Lilly LB, Selzner N, Bhat M, Sreeharsha B, Selzner M, Ghanekar A, Cattral MS, McGilvray ID, Greig PD, Renner EL, Grant DR, Sapisochin G. Ann Surg Oncol. 2017 Jul 3;24(7):1843-1851.
Clinical and virologic outcomes in high-risk adult Epstein-Barr virus mismatched organ transplant recipients.
Kumar D, Patil N, Husain S, Chaparro C, Bhat M, Kim SJ, Humar A. Clinical Transplantation. 2017 Jul;31(7):e13000.
Early Intervention With Live Donor Liver Transplantation Reduces Resource Utilization in NASH: The Toronto Experience.
Barbas AS, Goldaracena N, Dib MJ, Al-Adra DP, Aravinthan AD, Lilly LB, Renner EL, Selzner N, Bhat M, Cattral MS, Ghanekar A, McGilvray ID, Sapisochin G, Selzner M, Greig PD, Grant DR. Transplant Direct. 2017 May 10;3(6):e158.
Stereotactic body radiotherapy versus TACE or RFA as a bridge to transplant in patients with hepatocellular carcinoma. An intention-to-treat analysis.
Sapisochin G, Barry A, Doherty M, Fischer S, Goldaracena N, Rosales R, Russo M, Beecroft R, Ghanekar A, Bhat M, Brierley J, Greig PD, Knox JJ, Dawson LA, Grant DR. Journal of Hepatology. 2017 Feb 28;67(1):92-99.
Novel MELD Exception Point System for Hepatocellular Carcinoma based on Tumor Characteristics and Dynamics.
Bhat M, Ghali P, Dupont B, Hilzenrat R, Tazari M, Roy A, Chaudhury P, Alvarez F, Carrier M, Bilodeau M. Journal of Hepatology. 2017 Feb 6;66(2):374-381.
Incidence and Predictors of Advanced Liver Fibrosis by a Validated Serum Biomarker in Liver Transplant Recipients.
Bhat M, Rollet-Kurhajec K, Bhat A, Farag A, Deschenes M, Wong P, Ghali P, Sebastiani G. Can J Gastro. 2017 Jan;2017:4381864.
Normothermic Ex Vivo Liver Perfusion Using Steen Solution as Perfusate for Human Liver Transplantation-First North American Results.
Selzner M, Goldaracena N, Echeverri J, Kaths JM, Linares I, Selzner N, Serrick C, Marquez M, Sapisochin G, Renner EL, Bhat M, McGilvray ID, Lilly L, Greig PD, Tsien C, Cattral MS, Ghanekar A, Grant DR. Liver Transpl. 2016 Nov 24;22(11):1501-1508.
The Implication of the Intestinal Microbiome in Complications of Cirrhosis.
Bhat M, Renner E, Bhat V, Arendt BM, Humar A, Allard JP. World Journal of Hepatology. 2016 Sep;8(27):1128-1136.
Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells.
Bhat M, Yanagiya A, Graber T, Razumilava N, Bronk S, Zammit D, Zhao Y, Zakaria C, Metrakos P, Pollak M, Sonenberg N, Gores G, Jaramillo M, Morita M, Alain T. Oncotarget. 2016 Jul 18;8(31):50542-50556.
Decreased PCSK9 expression in Hepatocellular Carcinoma.
Bhat M, Deschenes M, Marcus V, Skill N, Bouteaud J, Tan X, Negi S, Awan Z, Aikin R, Kwan J, Amre R, Tabaries S, Hassanain M, Maluccio M, Siegel P, Metrakos P. BMC Gastroenterology. 2015 Dec:2015 Dec 16;15:176.
Portal vein encasement predicts neoadjuvant therapy response in liver transplantation for perihilar cholangiocarcinoma protocol.
Bhat M, Hathcock M, Kremers WK, Darwish Murad S, Schmit G, Martenson J, Alberts S, Rosen CB, Gores GJ, Heimbach J. Transplant International. 2015 Dec:2015 Dec;28(12):1383. [Epub ahead of print].
Serum fibrosis biomarkers predict death and graft loss in liver transplant recipients: a 20-year study. Liver Transplantation.
Bhat M, Ghali P, Bhat A, Rollet K, Wong P, Deschenes M, Sebastiani G. 2015 Nov:2015 Nov;21(11):1383.
Prevalence and predictors of sleep disturbance among liver diseases in long-term transplant survivors.
Bhat M, Wyse J, Ghali P, Hilzenrat N, Wong P, Moodie E, Deschenes M. Can J Gastroenterol Hepatol. 2015 Nov:2015 Dec;29(8):44. [Epub ahead of print].
Comparison Costs of ERCP and MRCP in Patients with Suspected Biliary Obstruction Based on a Randomized Trial.
Adam V, Bhat M, Romagnuolo J, da Silveira E, Reinhold C, Valois E, Martel M, Barkun JS, Barkun AN. Value in Health. 2015 Sep:2015 Sep;18(6):767-7.
Systematic review: Preventive and therapeutic applications of metformin in liver disease
Bhat A, Sebastiani G, Bhat M. World J Hepatology. 2015 Jun 28;7(12):1652-9.
Mammalian target of rapamycin inhibition after solid organ transplantation: can it, and does it, reduce cancer risk?
Bhat M, Watt K. Clinical Transplantation. 2015 Jun 10:2015 Jul;29(7):654-6.
Targeting the translation machinery in cancer.
Bhat M, Robichaud N, Hulea L, Pelletier J, Sonenberg N, Topisirovic I. Nature Reviews Drug Discovery. 2015 Mar 6:2015 Apr;14(4):261-7.
P53 inducible gene 3 (PIG3): A Potential Marker for HCC beyond Milan criteria.
Bhat M, Goldstein S, Tchervenkov J, et al. J Gastro Hep Research. 2015;4(1):1434-1438.
Prevention and Management of Chronic Hepatitis B.
Bhat M, Ghali P, Deschenes M, Wong P. International Journal of Preventive Medicine. 2014 Dec;5(Suppl 3):S200-7.
Metformin does not improve Survival in patients with a new diagnosis of Hepatocellular Carcinoma.
Bhat M, Chaiteerakij R, Harmsen W, Therneau T, Gores G, Roberts L. World J Gastroenterol. 2014 Nov 14;20(42):15750-5.
Tumour Necrosis Factor-Alpha Polymorphism Increases the Risk for Nonvariceal Upper Gastrointestinal Bleeding in Patients Taking Proton Pump Inhibitors.
Bhat M, Lu Y, Marcil V, Amre D, Martel M, Seidman EG, Barkun A. Can J Gastroenterol Hepatol. 2014 Oct;28(9):488.
Care of the Liver Transplant Patient.
Bhat M, Al-Busafi S, Ghali P, Wong P, Deschenes M. Can J of Gastro. 2014 Apr;28(4):213-9.
A care coordination program to optimize management of cirrhosis: real life applicability and feasibility in the context of Canadian health care system.
Carpentier S, Bhat M, Deschenes M, Wong P, Ghali P, Sebastiani G. Can J of Gastro. 2014 Apr;28(4):221-2.
Randomised clinical trial: MRCP-first vs. ERCP-first approach in patients with suspected biliary obstruction due to bile duct stones.
Bhat M, Romagnuolo J, da Silveira E, Reinhold C, Valois E, Martel M, Barkun JS, Barkun AN. Aliment Pharmacol Ther. 2013 Nov;38(9):1045-53.
Magnitude of change in alpha-fetoprotein in response to transarterial chemoembolization predicts survival in patients undergoing liver transplantation for hepatocellular carcinoma.
Bhat M, Hassanain M, Simoneau E, Tzimas GN, Chaudhury P, Deschenes M, Valenti D, Ghali P, Wong P, Cabrera T, Barkun J, Tchervenkov JI, Metrakos P. Curr Oncol. 2013 Oct;20(5):265-72.
The Dissemination Of Consensus Recommendations On The Management Of Non Variceal Upper Gastrointestinal Bleeding: A National Cluster Randomized Trial.
Barkun AN, Bhat M, Armstrong D, Dawes M, Donner A, Enns R, Martin J, Moayyedi P, Romagnuolo J, Tugwell P. Canadian Medical Association Journal. 2013 Feb 19;185(3):E156-66.
Preserving Flow in Liver Transplant Recipients: mTOR Inhibitors Everolimus and Sirolimus Are Not Peas From a Pod.
Bhat M, Charlton M. Am J Transplant. 2013;13:1633-1635.
The mTOR pathway in hepatic malignancies.
Bhat M, Nahum Sonenberg, Gores G. Hepatology. 2013;58(2):810-818.
eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies.
Alain T, Morita M, Fonseca BD, Yanagiya A, Siddiqui N, Bhat M, Zammit D, Marcus V, Metrakos P, Voyer LA, Gandin V, Liu Y, Topisirovic I, Sonenberg N. Cancer Res. 2012 Oct 24;72(24):6468-76.
Smoking Increases Recurrent Viral Hepatitis After Liver Transplantation.
Bhat M, Deschenes M, Martel M, Wong P, Metrakos P, Ghali PM. Liver Transpl. 2012 Jul;18(7):828-33.
Prediction and prevention of upper gastrointestinal bleeding after cardiac surgery: a case control study.
Bhat M, Larocque M, Amorim M, Herba K, Martel M, De Varennes B, Barkun A. Can J Gastroenterol. 2012 Jun;26(6):340-4.
Hepatitis B in Infected Healthcare workers: Public Safety at what cost?
Bhat M, Ghali P, Deschenes M, Wong P. Can J Gastroenterol. 2012 May;26(5):257-60.
Immunosuppression With Budesonide for Liver Transplant Recipients With Severe Infections.
Bhat M, Ghali P, Marcus V, Michel RP, Wong P, Metrakos P, Deschenes M. Liver Transpl. 2012 Feb;18(2):262-3.
Antioxidant Therapy in Non-Alcoholic Steatohepatitis: a review of the evidence.
Al-Busafi S, Bhat M, Ghali P, Wong P, Deschenes M. Hepat Res Treat. 2012;2012:947575.
Secondary intestinal lymphangiectasia due to multiple myeloma.
Bhat M, Laneuville P, Marliss E, Costea F, Marcus V, Seidman E, Bitton A. Gastrointestinal Endoscopy. 2011 Sep 17;74(3):718-20.
Acute Obstructive Pancreatitis caused by Migrated Balloon Gastrostomy Tube.
Bhat M, Bridges E. CMAJ. 2011 Aug 9;183(11):E759.
Phenotypic and genotypic characteristics of inflammatory bowel disease in French Canadians: comparison with a large North American repository.
Bhat M, Nguyen GC, Pare P, Lahaie R, Deslandres C, Bernard EJ, Aumais G, Jobin G, Wild G, Cohen A, Langelier D, Brant S, Dassopoulos T, McGovern D, Torres E, Duerr R, Regueiro M, Silverberg MS, Steinhart H, Griffiths AM, Elkadri A, Cho J, Proctor D, Goyette P, Rioux J, Bitton A. Am J Gastroenterol. 2009 Sep 1;104(9):2233-40.
Wheezes, blisters, bumps and runs: multisystem manifestations of a Crohn’s disease flare-up.
Bhat M, Dawson D. CMAJ. 2007 Sep 25;177(7):715-8.
Efficacy of methylphenidate in children with attention-deficit hyperactivity disorder and learning disabilities: a randomized crossover trial.
Grizenko N, Bhat M, Schwartz G, Ter-Stepanian M, Joober R. J Psychiatry Neurosci. 2006 Jan 1;31(1):46-51.